CV

General Information

Full Name Alexander Po-Yen Wu
Interests Graph machine learning, causal inference, biological networks, biomolecular design

Education

  • 2023
    PhD in Computational and Systems Biology
    Massachusetts Institute of Technology
  • 2018
    SM in Computational Biology and Quantitative Genetics
    Harvard University
  • 2016
    BS in Operations Research, Minor in Applied Mathematics
    Columbia University

Experience

  • Sept 2018-May 2023
    Graduate Research Assistant
    Computer Science and Artificial Intellience Laboratory, MIT
    • Graph machine learning and causal inference for studying single-cell gene regulatory dynamics
    • Enhancer-gene interactions for interpreting effects of noncoding disease variants on gene dysregulation
    • Causal TF-gene interactions using RNA velocity graphs to uncover patterns of gene regulatory timing
    • Single-cell multi-omic profiling of CRISPR perturbations to chromatin remodelers in cancer
    • Bayesian methods for reconstructing gene regulatory networks in small sample size settings
  • Jan 2023-June 2023
    Computational Sciences Intern
    Prime Medicine
    • Machine learning for prime editing
  • Jun 2022-Oct 2022
    Machine Learning Research Intern
    Twitter Cortex
    • Causal graph machine learning for improving the performance of graph attention networks
  • Jun 2018-Aug 2018
    Deep Learning Intern
    Quantum-Si
    • Machine learning on biological knowledge graphs for protein function prediction